An inhabited center since Roman times, on the banks of the river Ombrone, Poggio a Caiano is one of the best-known towns in the Montalbano area. First the Strozzi and then the Medici populated the area, an important point of reference for trade and communication.
The town strongly identifies with its magnificent Villa Medicea, the mansion commissioned by Lorenzo the Magnificent, born with the name Ambra, and shrouded in a myth that gives the place further charm: the nymph who bore this name was helped by the goddess Diana to flee to this hill, to save herself from Ombrone, who tormented her.